Meatloaf Seasoning Recipe
Oct 24, 2022, Updated Apr 12, 2025
This post may contain affiliate links. Please read our disclosure policy.
My simple meatloaf seasoning recipe will add incredible flavor to your homemade meatloaf. The perfect blend of spices will take your meatloaf recipe from good to out of this world. Use this spice mix for the best meatloaf ever!

We are a meatloaf family. I grew up eating it and now my kids love having it for dinner. Over the years of making meatloaf I’ve found that the secret to the best, most flavorful meatloaf ever is this meatloaf seasoning mix and this meatloaf sauce recipe.
It’s easy to make your own seasoning mixes at home. You don’t need to use a store bought packet of seasoning because you can make your own in minutes without all of those extra preservatives.
This meatloaf spice blend is one that I make and keep in my spice cabinet so I have it ready when I make meatloaf, burgers, and more.
Use this seasoning for recipes like one pound meatloaf, air fryer meatloaf, Lipton onion soup meatloaf, burgers, and even meatballs.
Why you’ll love this recipe
- Amazing flavor. This blend adds so much wonderful flavor to your meatloaf.
- Fast to make. You can whip up this seasoning blend in less than 5 minutes.
- Can make a big batch and store for up to 6 months.
Ingredients
Just a few simple spices are needed for this meatloaf seasoning blend. This recipe works great with 2 pounds of ground meat.

- Salt – Salt enhances all of the other spices.
- Ground Black Pepper – Adds a subtle heat to the meatloaf. You can adjust the amount to your taste.
- Paprika – Gives the meatloaf a smoky-sweet flavor.
- Ground Dried Mustard – Adds a little bit of tanginess.
- Onion Powder – Gives you that great onion flavor.
- Garlic Powder – This is a must for this spice blend.
- Dried Thyme – An earthy seasoning that pairs great with ground beef.
- Dried Basil – Another earthy flavor that brings everything together.
How to make homemade meatloaf seasoning
- Mix: Place all of the spices in a bowl. Stir until combined.
- Add to your meatloaf recipe or store in an airtight container for later use.
Recipe variations
You can change up the meatloaf seasoning spices for personal preference. A few suggestions are:
- Italian seasoning – Replace the basil and thyme with Italian seasoning.
- Spicy – Like a little heat to your meatloaf? Try stirring in 1/4 teaspoon of cayenne pepper or replace basil and thyme with Cajun seasoning.
How to season meatloaf
Add your seasonings in when making your ground meat mixture. Make sure to combine the meatloaf ingredients well without over mixing so that the meatloaf doesn’t become tough.

Heather’s recipe tips
- Use fresh spices. If you are planning on storing any leftover seasoning, I would recommend using fresh spices for the best flavor.
- This will work with any ground meat. You can use it with beef, chicken, turkey, or even beans.
- Make a double or triple batch to store for later use.
Storage instructions
Store: If you aren’t ready to use the meatloaf spices and need to store it, place in an airtight container like a jar and store in a cool dark place like a pantry or cabinet. The seasoning mix will last up to 6 months.
So forget buying the pre-made meatloaf seasoning, you can easily make your own spice blend at home.

Frequently asked questions
Yes, this seasoning mix will last for about 6 months.
I recommend about 3 teaspoons of seasoning for one pound of beef.
Yes, you can double or triple this recipe.
More seasoning mixes
- Chicken Taco Seasoning
- Steak Seasoning
- Chili Seasoning
- French Fry Seasoning
- Red Robin seasoning
- Wingstop fry seasoning
- Zaxbys fry seasoning

Meatloaf Seasoning
Ingredients
- 1 teaspoon salt
- 1 teaspoon ground black pepper
- 2 teaspoons paprika
- 1 1/2 teaspoons ground dried mustard
- 1 teaspoon onion powder
- 1 teaspoon garlic powder
- 1/2 teaspoon dried thyme
- 1/2 teaspoon dried basil
Instructions
- Place all of the ingredients in a bowl and stir to combine.
- Use for a two pound meatloaf or place in an airtight container and store for later use.
- Note: When making the meatloaf, add in the seasoning mixture when mixing the ground meat.
Video
Notes
- Italian seasoning – Replace the basil and thyme with Italian seasoning.
- Spicy – Like a little heat to your meatloaf? Try stirring in 1/4 teaspoon of cayenne pepper or replace basil and thyme with Cajun seasoning.
Nutrition
Nutrition information is automatically calculated, so should only be used as an approximation.















How long do I cook the meatloaf and on what temperature?
Thank You!
Will make tomorrow.
Can I substitute marjoram for the thyme?
Thank you.
“You will seek me and find me when you seek me with all your heart ” [Jeremiah 29:13]
Looks good but how much do you use for 2 pounds of ground beef?
I use the whole recipe to season 2 pounds of ground beef.
Delicious